RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00133 |
| Gene Symbol | RPGF3 | |
| Gene Description | Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI) | |
| Gene Name in Paper | RAPGEF3 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000389212 ENST00000395358 ENST00000405493 ENST00000449771 ENST00000549151 | |
| UniProt ID | O95398 | |
| Entrez Gene ID | 10411 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |