Vhf00123 details

Gene vhfRNAi AccessionVhf00123
Gene SymbolLCE1C
Gene DescriptionLate cornified envelope protein 1C (Late envelope protein 3)
Gene Name in PaperLCE1C
GroupRestriction Factor
Ensembl Gene IDENST00000607093  
UniProt IDQ5T751
Entrez Gene ID353133
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)