RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00093 |
| Gene Symbol | UBC9 | |
| Gene Description | SUMO-conjugating enzyme UBC9 (EC 6.3.2.-) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18) | |
| Gene Name in Paper | UBE2I | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000325437 ENST00000355803 ENST00000397514 ENST00000397515 ENST00000403747 ENST00000406620 ENST00000566587 | |
| UniProt ID | P63279 | |
| Entrez Gene ID | 7329 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |