RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00042 |
| Gene Symbol | NR1I3 | |
| Gene Description | Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67) | |
| Gene Name in Paper | NR1I3 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000367979 ENST00000367980 ENST00000367981 ENST00000367982 ENST00000367983 ENST00000367984 ENST00000367985 ENST00000412844 ENST00000428574 ENST00000437437 ENST00000442691 ENST00000504010 ENST00000505005 ENST00000508740 ENST00000511676 ENST00000512372 | |
| UniProt ID | Q14994 | |
| Entrez Gene ID | 9970 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |