Vhf00025 details

Gene vhfRNAi AccessionVhf00025
Gene SymbolF101B
Gene DescriptionFilamin-interacting protein FAM101B (Protein FAM101B) (Regulator of filamin protein B) (RefilinB)
Gene Name in PaperMGC45871
GroupRestriction Factor
Ensembl Gene IDENST00000329099  
UniProt IDQ8N5W9
Entrez Gene ID359845
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)