Vhf00009 details

Gene vhfRNAi AccessionVhf00009
Gene SymbolRTBDN
Gene DescriptionRetbindin
Gene Name in PaperRTBDN
GroupRestriction Factor
Ensembl Gene IDENST00000322912  ENST00000393233  ENST00000458671  ENST00000592204  
UniProt IDQ9BSG5
Entrez Gene ID83546
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
Score-19.3
UnitFold change
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)