Vhf00004 details

Gene vhfRNAi AccessionVhf00004
Gene SymbolTROAP
Gene DescriptionTastin (Trophinin-assisting protein) (Trophinin-associated protein)
Gene Name in PaperTROAP
GroupRestriction Factor
Ensembl Gene IDENST00000257909  ENST00000380327  ENST00000548311  
UniProt IDQ12815
Entrez Gene ID10024
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
Score-25.1
UnitFold change
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)