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ViralEpi v1.0 Overview
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ViralEpi v1.0 is the resource for epigenomic methylation profile (Methylome) of viruses i.e. two double stranded DNA viruses namely, Epstein Barr Virus (EBV) and Hepatitis B virus (HBV). It is integrated with user-friendly EpiGenome browser for interactive visualization.
There are various resources available to provide host methylation events. However, till now no one has focused on very important aspect of viral epigenomic events. We have compiled viral methylome especially of EBV and HBV from various studies pertaining to diverse clinical samples, cell lines and diseased conditions.
It addresses methylation events from important diseases including various carcinomas such as Burkitt lymphoma (BL), Hodgkin Disease (HD), Nasal lymphoma (NL), Post-transplant lymphoproliferative disease (PTLD), Nasopharangeal carcinoma (NPC), Infectious Mononucleosis (IM), Lymphoproliferative disease (LPD) caused by Epstein Barr Virus and Hepatitis, Hepatocellular Carcinoma (HCC), Liver Cirrhosis caused by Hepatitis B Virus.
It mainly includes diverse knowledge of viral methylome i.e. methylation sites, Methylation status and percentage, specimen or sample type, cell lines, sample size, disease/histology, detection techniques, references etc.
It is freely available at http://bioinfo.imtech.res.in/manojk/viralepi for the research community working in the area for epigenomics
