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Record - 1 of 6   [TOP]
Compound IDNVIC0019
Compound Structure
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InhibitorRibavirin
PubChem ID 37542
Drug Bank ID
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207 g/mol
TargetReplication
Assay TypeCPE reduction assay
Assay DescriptionCPE Assay
Assay Source
Cell TypeVero E6 cells
Outcomeinhibit replication
IC50 (in nM)
EC50 (in nM)
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3.0
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472238/
PubMed ID [Source Literature] 16641448
Curatorkanikatuteja@gmail.com

                  
Record - 2 of 6   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank ID
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207 g/mol
Target
Assay Type
Assay Description
Assay Source
Cell Type
Outcome
IC50 (in nM)
EC50 (in nM)
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3.0
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pubmed/11409437
PubMed ID [Source Literature] 11409437
Curatorkanikatuteja@gmail.com

                  
Record - 3 of 6   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank ID
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207 g/mol
TargetRNA dependent RNA Polymerase
Assay Type
Assay Description
Assay Source
Cell Type
Outcomeblock virus replication through error catastrophe
IC50 (in nM)
EC50 (in nM)
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3.0
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428208/
PubMed ID [Source Literature] 26029193
Curatornishisharmacool14@gmail.com

                  
Record - 4 of 6   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
Inhibitorribavirin
PubChem ID 37542
Drug Bank ID
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207 g/mol
Target
Assay Typedose–response assays
Assay Descriptionnon-linear regression analysis
Assay SourceSigma Chemical Company (St. Louis, MO, USA).
Cell TypeHeLa
Outcomeeffectively reduce the spread and infection of NiV
IC50 (in nM)4180
EC50 (in nM)
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3.0
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888097/
PubMed ID [Source Literature] 19889926
Curatornishisharmacool14@gmail.com

                  
Record - 5 of 6   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank ID
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207 g/mol
Target
Assay TypeBSL4 HTS assay
Assay DescriptionHRP-chemiluminescent
Assay Source
Cell TypeVero cells
Outcome
IC50 (in nM)3356
EC50 (in nM)3356
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3.0
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
PubMed ID [Source Literature] 18313148
Curatorkanikatuteja@gmail.com

                  
Record - 6 of 6   [TOP]
Compound IDNVIC0019
Compound Structure
DOWNLOAD:
InhibitorRibavirin
PubChem ID 37542
Drug Bank ID
ChemSpider ID 34439
SMILESC1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
Molecular Weight (in g/mol)244.207 g/mol
Target
Assay TypeBSL2 HTS assay
Assay Descriptionfluorescent immunodetection
Assay Source
Cell TypeVero cells
Outcome
IC50 (in nM)6041
EC50 (in nM)6041
H-bond Acceptor7
H-bond Donor4
No. of Rotatable Bond Count3
XLogP-3.0
PSA143.72
Reference(s)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653211/
PubMed ID [Source Literature] 18313148
Curatorpriyankapaul008@gmail.com