Frequently Asked Questions

Q1. What is AntiVIRmiR?

AntiVIRmiR is a computational resource that includes data for host/virus miRNA during the viral infection. AntiVIRmiR resource is divided into four sections viz. DEmiRVIR, AntiVmiR,VIRmiRNA2 and VIRmiRTar2. ‘VIRmiRNA2€™ section includes 3340 entries for experimentally validated viral miRNAs obtained from 56 viruses. ‘VIRmiRTar2’ has 7726 experimentally validated targets for viral miRNAs against 21 viruses. ‘AntiVmiR’ section incorporates 1642 entries for host miRNAs that show antiviral as well as proviral activity for 34 viruses. While in ‘DEmiRVIR’ section, we have collected the data for host/viral miRNAs that are differentially expressed and are obtained using high-throughput methods. This section includes 10,033 differentially expressed host/viral miRNAs for 21 viruses.

Q2. What is the use of this database ?

The resource will be useful for understanding host-viral interactions and development of antiviral therapeutics.

Q3. How many sub-databases are there in AntiVIRmiR?

There are four sub-databases-
(i) VIRmiRNA2- It shows the virus encoded miRNAs.
(ii) VIRmiRTa2r- It shows the viral miRNAs with their target protein.
(iii) AntiVmiR- It contains the antiviral miRNA entries with its target.
(iv) DEmiRVIR- It contains the data for host/viral miRNAs that are differentially expressed and are obtained using high-throughput methods.

Q4. What are the fields of AntiVIRmiR?

These are as follows- (i) miRNA name, (ii) Virus name, (iii) miRNA sequence, pre-miRNA sequence (iv) Target gene, (v) Organism, (vi) Cell line, (vii) Experimental method, (viii) Length, (ix) GC content, (x) Uniprot id, (xi) miRNA Expression, (xii) Score, (xiii)Pubmed id .

Q5. What type of analyses is provided in the resource ?

We have performed network interaction analyses using Cytoscape Software that was performed for DEmiRVIR, AntiVmiR and VIRmiRTar2 data.

Q6. What are the tools in AntiVIRmiR?

There are three tools used in BLAST, Tar-Find and Map.

Q7. How many entries are there in VIRmiRNA2 sub-database ?

‘VIRmiRNA2’ section includes 3340 entries for experimentally validated viral miRNAs obtained from 56 viruses.

Q8. How many entries are there in VIRmiRTar2 sub-database ?

‘VIRmiRTar2’ has 7726 experimentally validated targets for viral miRNAs against 21 viruses.

Q9. How many entries are there in AntiVmiR sub-database ?

‘AntiVmiR’ section incorporates 1642 entries for host miRNAs that show antiviral as well as proviral activity for 34 viruses.

Q10. How many entries are there in DEmiRVIR sub-database ?

‘DEmiRVIR’ section includes 10,033 differentially expressed host/viral miRNAs for 21 viruses.

Q11. Is this resource freely available ?

Yes, this database is freely available through this url: http://bioinfo.imtech.res.in/manojk/antivirmir/.