Using CYTOSCAPE software, we have developed interaction map of three sections, viz. DEmiRVIR, AntiVmiR and VIRmiRTar2. In DEmiRVIR, network is developed for host (human) miRNA that are upregulated, downregulated or both in different viruses. In AntiVmiR, we have developed the interaction map for host miRNA found common in different viruses. While in VIRmiRTar2 section, network is developed for viral miRNAs with their target found in different viruses. Networks can be explored by clicking on the individual analysis.
Note:
In DEmiRVIR, cytoscape map is represented in 4 different colors i.e. red for virus having upregulated miRNA, purple for virus having downregulated miRNA, green for viruses that has both up or down-regulated miRNAs and pink for miRNA.
In AntiVmiR, cytoscape map is represented in 2 different colors i.e. red and pink for virus and miRNA respectively.
While in VIRmiRTar2, the domains of cytoscape map is represented in 3 different colors i.e. red, pink and green for virus, miRNA and target.
We are providing general view of map, which can be changed by the user through the options provided in the window like visual style and layout.