Chemical Clustering

The chemical clustering was performed through C-SPADE by employing extended-connectivity fingerprint 4 (ECFP 4) on 95 compounds used for the development of anti-nipah prediction server along with their IC50 values. The chemical dendrogram suggests the diversity in the anti-Nipah compounds due to the variability in functional group. As few instances showed the co-occurence of highly effective (low IC50 vlaues) and least effective (high IC50 values) inhibitiors.The chemicals dendogram of the anti-Nipah compounds are shown as: