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Important resources for CRISPR studies on the web

S. No.

Resource

Year

Description

Working URL

Publication

1

CrisprGE

2015

A central hub of CRISPR/Cas-based genome editing.

http://crdd.osdd.net/servers/crisprge/

Database (Oxford)

2

sgRNA scorer

2015

In vivo library-on-library methodology to simultaneously assess single guide RNA (sgRNA)
activity across ~1,400 genomic loci

https://crispr.med.harvard.edu/sgRNAScorer/

Nature Methods

3

WU-CRISPR

2015

characteristics of functional guide RNAs for the CRISPR/Cas9 system

http://crispr.wustl.edu/

Genome biology

4

CrisprScan

2015

Designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo

http://www.crisprscan.org/

Nature Methods

5

sgRNA designer

2014

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation

http://www.broadinstitute.org/rnai/public/analysis-tools/sgrna-design

Nature Biotechnology

6

E-CRISP

2014

CRIPSR target site prediction tool

http://www.e-crisp.org/E-CRISP/

Nature Methods

7

CHOPCHOP

2014

Web tool for designing of CRISPR/Cas9 and TALENs

https://chopchop.rc.fas.harvard.edu/

Nucleic Acids Res.

8

CRISPRstrand

2014

Repeat orientation prediction tool to determine crRNA encoding strand at CRISPR loci

http://rna.informatik.uni-freiburg.de/CRISPRmap/Input.jsp

Bioinformatics

9

sgRNAcas9

2014

A software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites

http://www.biootools.com/

PLoS One

10

SSFinder

2014

CRISPR-Cas target site prediction tool

https://code.google.com/p/ssfinder/

Biomed Res Int.

11

CRISPR-P

2014

A Web Tool for Synthetic Single-Guide RNA Design of CRISPR-System in Plants

http://cbi.hzau.edu.cn/crispr/

Mol Plant.

12

GT-Scan

2014

Identifying unique genomic targets

http://gt-scan.braembl.org.au/gt-scan/

Bioinformatics

13

CasOT

2014

A genome-wide Cas9/gRNA off-target searching tool

http://eendb.zfgenetics.org/casot/

Bioinformatics

14

Cas-OFFinder

2014

A fast and versatile algorithm that searches for potential off target sites of Cas9 Rna guided
endonucleases

http://www.rgenome.net/cas-offinder

Bioinformatics

15

CRISPRTarget

2013

Bioinformatics tool that helps in prediction and analysis of targets of CRISPR RNAs.
It compares the Crispr sequences with the viral genomes

http://bioanalysis.otago.ac.nz/CRISPRTarget/crispr_analysis.html

RNA Biol.

16

CRISPI

2009

Database that finds CRISPRs in given genomes and calculates its similarity with other sequences

http://crispi.genouest.org/

Bioinformatics

17

CRISPRdb

2007

Database of finding CRISPRs and repeat element extraction tool

http://crispr.u-psud.fr/crispr/

BMC Bioinformatics

18

CRISPRdirect

2014

Rational design of CRISPR/Cas target

http://crispr.dbcls.jp

Bioinformatics