Chemical, Structural and Biological details of Quorum Sensing Signaling Molecule

QSSM_0523




Chemical Information
QSSM_ID:QSSM_0523
SigMol name:N-(3-hydroxyoctanoyl)-L-homoserine lactone       [Link]
Abbreviation:OHC8-HSL
IUPAC name:3-Hydroxy-N-(2-oxotetrahydro-3-furanyl)octanamide
SMILES:O=C1OCCC1NC(=O)CC(O)CCCCC
Molecular Formula:C12H21NO4
Molecular Weight (g/mol):243.3
Structural Information:[Link]
Biological Information
Name of AHL in article: N-(3-hydroxyoctanoyl)-L-homoserine lactone
Synthase gene:bmaI
Recipient gene: bmaR
Organism:Burkholderia mallei      [Link to taxonomy browser]
Strain:RJ16
Preliminary assay:AHL bioassay
Bacterial strain used in Preliminary assay:Agrobacterium tumefaciens NTL4
Identification assay:MS-MS
Application:biosynthesis of virulence factors
Features of bacteria: etiologic agent of glanders, a gram-negative, oxidase-positive, nonmotile bacillus that is an obligate animal pathogen
Reference:15501791     [Link to PubMed]

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