Chemical, Structural and Biological details of Quorum Sensing Signaling Molecule

QSSM_0042




Chemical Information
QSSM_ID:QSSM_0042
SigMol name:N-(3-Hydroxydodecanoyl)-L-homoserine lactone       [Link]
Abbreviation:OHC12-HSL
IUPAC name:3-Hydroxy-N-[(3S)-2-oxotetrahydro-3-furanyl]dodecanamide
SMILES:CCCCCCCCCC(CC(=O)N[C@H]1CCOC1=O)O
Molecular Formula:C16H29NO4
Molecular Weight (g/mol):299.21
Structural Information:[Link]
Biological Information
Name of AHL in article: N-(3-hydroxydodecanoyl)-L- homoserine lactone (OH-dDHL)
Synthase gene:abaI
Recipient gene: abaR
Organism:Acinetobacter baumannii      [Link to taxonomy browser]
Strain:M2
Preliminary assay:TLC-AHL bioassay (Thin-layer chromatogrpahy
Bacterial strain used in Preliminary assay:Agrobacterium tumefaciens traG-lacZ
Identification assay:LC-MS/MS
Application:biofilm development
Features of bacteria: important nosocomial pathogen
Reference:18281398     [Link to PubMed]

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