HPVomics

A therapeutic and epitome resource for Human Papillomaviruses

Efficient putative LR-HPVs E8^E2 protein epitopes (MHC-II Binders)

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S.No.	HPV type	Target region	Peptide seuences	Start	End	Allele	Method	Percentile rank
1	HPV43	E8^E2	LKCFRYRLNKHKHLF	113	127	HLA-DRB5*01:01	Consensus	0.04
2	HPV43	E8^E2	ALKCFRYRLNKHKHL	112	126	HLA-DRB5*01:01	Consensus	0.07
3	HPV43	E8^E2	KCFRYRLNKHKHLFA	114	128	HLA-DRB5*01:01	Consensus	0.07
4	HPV54	E8^E2	IVHFKGEPNTLKCFR	97	111	HLA-DRB5*01:01	Consensus	0.11
5	HPV72	E8^E2	CFRYRLQQSVPNLFL	124	138	HLA-DRB1*07:01	Consensus	0.11
6	HPV43	E8^E2	NALKCFRYRLNKHKH	111	125	HLA-DRB5*01:01	Consensus	0.13
7	HPV43	E8^E2	CFRYRLNKHKHLFAD	115	129	HLA-DRB5*01:01	Consensus	0.15
8	HPV72	E8^E2	KCFRYRLQQSVPNLF	123	137	HLA-DRB1*07:01	Consensus	0.15
9	HPV54	E8^E2	VHFKGEPNTLKCFRQ	98	112	HLA-DRB5*01:01	Consensus	0.18
10	HPV72	E8^E2	FRYRLQQSVPNLFLK	125	139	HLA-DRB1*07:01	Consensus	0.2
11	HPV54	E8^E2	PIVHFKGEPNTLKCF	96	110	HLA-DRB5*01:01	Consensus	0.23
12	HPV72	E8^E2	QQARDICNSHGAPII	99	113	HLA-DRB1*13:02	Consensus	0.25
13	HPV72	E8^E2	QARDICNSHGAPIIH	100	114	HLA-DRB1*13:02	Consensus	0.25
14	HPV72	E8^E2	ARDICNSHGAPIIHL	101	115	HLA-DRB1*13:02	Consensus	0.25
15	HPV72	E8^E2	RDICNSHGAPIIHLK	102	116	HLA-DRB1*13:02	Consensus	0.25
16	HPV40	E8^E2	QRSDFLAIVKIPKTI	161	175	HLA-DRB5*01:01	Consensus	0.26
17	HPV40	E8^E2	RSDFLAIVKIPKTIK	162	176	HLA-DRB5*01:01	Consensus	0.26
18	HPV40	E8^E2	SDFLAIVKIPKTIKH	163	177	HLA-DRB5*01:01	Consensus	0.26
19	HPV40	E8^E2	VQQRSDFLAIVKIPK	159	173	HLA-DRB1*11:01	Consensus	0.26
20	HPV40	E8^E2	QQRSDFLAIVKIPKT	160	174	HLA-DRB1*11:01	Consensus	0.26
21	HPV40	E8^E2	QRSDFLAIVKIPKTI	161	175	HLA-DRB1*11:01	Consensus	0.26
22	HPV40	E8^E2	RSDFLAIVKIPKTIK	162	176	HLA-DRB1*11:01	Consensus	0.26
23	HPV40	E8^E2	SDFLAIVKIPKTIKH	163	177	HLA-DRB1*11:01	Consensus	0.26
24	HPV40	E8^E2	DFLAIVKIPKTIKHS	164	178	HLA-DRB1*11:01	Consensus	0.26
25	HPV40	E8^E2	FLAIVKIPKTIKHSL	165	179	HLA-DRB1*11:01	Consensus	0.26
26	HPV40	E8^E2	FLAIVKIPKTIKHSL	165	179	HLA-DRB5*01:01	Consensus	0.26
27	HPV42	E8^E2	EAQRNLFLNTVKIPS	179	193	HLA-DRB1*11:01	Consensus	0.26
28	HPV42	E8^E2	AQRNLFLNTVKIPSG	180	194	HLA-DRB1*11:01	Consensus	0.26
29	HPV42	E8^E2	QRNLFLNTVKIPSGI	181	195	HLA-DRB1*11:01	Consensus	0.26
30	HPV42	E8^E2	RNLFLNTVKIPSGIK	182	196	HLA-DRB1*11:01	Consensus	0.26
31	HPV42	E8^E2	NLFLNTVKIPSGIKS	183	197	HLA-DRB1*11:01	Consensus	0.26
32	HPV43	E8^E2	ANALKCFRYRLNKHK	110	124	HLA-DRB5*01:01	Consensus	0.26
33	HPV44	E8^E2	SSSSTTTTLAQASST	25	39	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.29
34	HPV44	E8^E2	HSSSSTTTTLAQASS	24	38	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.3
35	HPV44	E8^E2	SSSTTTTLAQASSTL	26	40	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.3
36	HPV43	E8^E2	FRYRLNKHKHLFADV	116	130	HLA-DRB5*01:01	Consensus	0.31
37	HPV44	E8^E2	SHSSSSTTTTLAQAS	23	37	HLA-DQA1*01:02/DQB1*06:02	Consensus	0.35
38	HPV54	E8^E2	HFKGEPNTLKCFRQR	99	113	HLA-DRB5*01:01	Consensus	0.37
39	HPV44	E8^E2	AKYKTLFVAASSTWR	126	140	HLA-DRB5*01:01	Consensus	0.38
40	HPV44	E8^E2	KYKTLFVAASSTWRW	127	141	HLA-DRB5*01:01	Consensus	0.38
41	HPV44	E8^E2	YKTLFVAASSTWRWT	128	142	HLA-DRB5*01:01	Consensus	0.38
42	HPV44	E8^E2	KTLFVAASSTWRWTC	129	143	HLA-DRB5*01:01	Consensus	0.38
43	HPV44	E8^E2	TLFVAASSTWRWTCS	130	144	HLA-DRB5*01:01	Consensus	0.38
44	HPV44	E8^E2	LFVAASSTWRWTCSD	131	145	HLA-DRB5*01:01	Consensus	0.38
45	HPV44	E8^E2	FVAASSTWRWTCSDT	132	146	HLA-DRB5*01:01	Consensus	0.38
46	HPV72	E8^E2	RYRLQQSVPNLFLKA	126	140	HLA-DRB1*07:01	Consensus	0.4
47	HPV70	E8^E2	RYRLRKFNSLYENIS	102	116	HLA-DRB1*04:05	Consensus	0.41
48	HPV54	E8^E2	TPIVHFKGEPNTLKC	95	109	HLA-DRB5*01:01	Consensus	0.42
49	HPV70	E8^E2	YRLRKFNSLYENISC	103	117	HLA-DRB1*04:05	Consensus	0.42
50	HPV72	E8^E2	TQQARDICNSHGAPI	98	112	HLA-DRB1*13:02	Consensus	0.45
51	HPV44	E8^E2	PKVTYKVGYMSLQLL	173	187	HLA-DRB4*01:01	Consensus	0.51
52	HPV43	E8^E2	CFRYRLNKHKHLFAD	115	129	HLA-DRB1*11:01	Consensus	0.52
53	HPV72	E8^E2	IIHLKGEPNKLKCFR	112	126	HLA-DRB5*01:01	Consensus	0.54
54	HPV43	E8^E2	FRYRLNKHKHLFADV	116	130	HLA-DRB1*11:01	Consensus	0.63
55	HPV54	E8^E2	LKCFRQRIQKYKHLF	107	121	HLA-DRB5*01:01	Consensus	0.63
56	HPV43	E8^E2	KCFRYRLNKHKHLFA	114	128	HLA-DRB1*11:01	Consensus	0.69
57	HPV54	E8^E2	TTPIVHFKGEPNTLK	94	108	HLA-DRB5*01:01	Consensus	0.69
58	HPV54	E8^E2	FKGEPNTLKCFRQRI	100	114	HLA-DRB5*01:01	Consensus	0.69
59	HPV72	E8^E2	QQARDICNSHGAPII	99	113	HLA-DRB1*07:01	Consensus	0.7
60	HPV72	E8^E2	YRLQQSVPNLFLKAS	127	141	HLA-DRB1*07:01	Consensus	0.7
61	HPV81	E8^E2	ANKLKCLRYRLRSSV	115	129	HLA-DRB1*11:01	Consensus	0.72
62	HPV61	E8^E2	KCFRYRLQHSVPELF	121	135	HLA-DRB1*07:01	Consensus	0.73
63	HPV72	E8^E2	IHLKGEPNKLKCFRY	113	127	HLA-DRB5*01:01	Consensus	0.78
64	HPV54	E8^E2	TLKCFRQRIQKYKHL	106	120	HLA-DRB5*01:01	Consensus	0.81
65	HPV81	E8^E2	NKLKCLRYRLRSSVP	116	130	HLA-DRB1*11:01	Consensus	0.81
66	HPV11	E8^E2	ILKWKLQRSTVREVS	3	17	HLA-DRB5*01:01	Consensus	0.84
67	HPV11	E8^E2	MAILKWKLQRSTVRE	1	15	HLA-DRB5*01:01	Consensus	0.86
68	HPV11	E8^E2	AILKWKLQRSTVREV	2	16	HLA-DRB5*01:01	Consensus	0.86
69	HPV11	E8^E2	LKWKLQRSTVREVSI	4	18	HLA-DRB5*01:01	Consensus	0.86
70	HPV11	E8^E2	KWKLQRSTVREVSIA	5	19	HLA-DRB5*01:01	Consensus	0.86
71	HPV11	E8^E2	WKLQRSTVREVSIAE	6	20	HLA-DRB5*01:01	Consensus	0.86
72	HPV42	E8^E2	AYNVPIQTSPPRKRY	56	70	HLA-DRB5*01:01	Consensus	0.86
73	HPV42	E8^E2	YNVPIQTSPPRKRYR	57	71	HLA-DRB5*01:01	Consensus	0.86
74	HPV42	E8^E2	NVPIQTSPPRKRYRQ	58	72	HLA-DRB5*01:01	Consensus	0.86
75	HPV42	E8^E2	VPIQTSPPRKRYRQC	59	73	HLA-DRB5*01:01	Consensus	0.86
76	HPV72	E8^E2	TQQARDICNSHGAPI	98	112	HLA-DRB1*07:01	Consensus	0.94
77	HPV70	E8^E2	KNGLKCLRYRLRKFN	95	109	HLA-DRB1*11:01	Consensus	0.99
78	HPV72	E8^E2	FRYRLQQSVPNLFLK	125	139	HLA-DRB3*02:02	NetMHCIIpan	0.03
79	HPV72	E8^E2	CFRYRLQQSVPNLFL	124	138	HLA-DRB3*02:02	NetMHCIIpan	0.04
80	HPV72	E8^E2	RYRLQQSVPNLFLKA	126	140	HLA-DRB3*02:02	NetMHCIIpan	0.06
81	HPV81	E8^E2	CLRYRLRSSVPHLFV	120	134	HLA-DRB3*02:02	NetMHCIIpan	0.06
82	HPV81	E8^E2	LRYRLRSSVPHLFVN	121	135	HLA-DRB3*02:02	NetMHCIIpan	0.06
83	HPV72	E8^E2	KCFRYRLQQSVPNLF	123	137	HLA-DRB3*02:02	NetMHCIIpan	0.07
84	HPV81	E8^E2	RYRLRSSVPHLFVNA	122	136	HLA-DRB3*02:02	NetMHCIIpan	0.07
85	HPV81	E8^E2	KCLRYRLRSSVPHLF	119	133	HLA-DRB3*02:02	NetMHCIIpan	0.2
86	HPV40	E8^E2	KCFRYRLGKVSHLFC	118	132	HLA-DRB3*02:02	NetMHCIIpan	0.31
87	HPV43	E8^E2	KCFRYRLNKHKHLFA	114	128	HLA-DRB3*02:02	NetMHCIIpan	0.31
88	HPV40	E8^E2	LKCFRYRLGKVSHLF	117	131	HLA-DRB3*02:02	NetMHCIIpan	0.32