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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
988330

Cc1ccc(nc1)Nc1nc2c([nH]1)cccc2		 Formula:C13H12N4
Mol: 224.26
Heavy atoms:17
Aromatic heavy atoms: 15
Fraction Csp3: 0.08
Rotatable bonds: 2
H-bond acceptors: 2
H-bond donors: 2
MR: 68.40
TPSA: 53.60
ILOGP:1.72
XLOGP3: 2.99
WLOGP: 3.01
MLOGP: 2.16
Silicos ITLogP: 2.69
Consensus LogP: 2.51
 ESOL
LogS:-3.64
Solubility(mg/ml): 0.052000
Solubility(mol/l):0.000232
Class:Soluble

Ali
LogS:-3.78
Solubility(mg/ml): 0.037300
Solubility(mol/l): 0.000166
Class:Soluble

SilicosIT
LogS:-5.50
Solubility(mg/ml): 0.000706
Solubility(mol/l): 0.000003
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  Yes
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -5.55
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.02