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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
96231931

O=C(c1n[nH]c2c1CCCCC2)Nc1nc[nH]n1		 Formula:C11H14N6O
Mol: 246.27
Heavy atoms:18
Aromatic heavy atoms: 10
Fraction Csp3: 0.45
Rotatable bonds: 3
H-bond acceptors: 4
H-bond donors: 3
MR: 64.98
TPSA: 99.35
ILOGP:0.18
XLOGP3: 1.55
WLOGP: 0.86
MLOGP: 0.82
Silicos ITLogP: 1.68
Consensus LogP: 1.02
 ESOL
LogS:-2.56
Solubility(mg/ml): 0.684000
Solubility(mol/l):0.002780
Class:Soluble

Ali
LogS:-3.25
Solubility(mg/ml): 0.140000
Solubility(mol/l): 0.000568
Class:Soluble

SilicosIT
LogS:-3.61
Solubility(mg/ml): 0.060200
Solubility(mol/l): 0.000244
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.70
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.71