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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
95442571

N#Cc1ccc2c(c1)nc([nH]2)c1ccc(cn1)C		 Formula:C14H10N4
Mol: 234.26
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.07
Rotatable bonds: 1
H-bond acceptors: 3
H-bond donors: 1
MR: 69.01
TPSA: 65.36
ILOGP:2.17
XLOGP3: 2.20
WLOGP: 2.80
MLOGP: 1.27
Silicos ITLogP: 3.47
Consensus LogP: 2.38
 ESOL
LogS:-3.23
Solubility(mg/ml): 0.138000
Solubility(mol/l):0.000590
Class:Soluble

Ali
LogS:-3.21
Solubility(mg/ml): 0.146000
Solubility(mol/l): 0.000621
Class:Soluble

SilicosIT
LogS:-5.54
Solubility(mg/ml): 0.000682
Solubility(mol/l): 0.000003
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -6.17
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.15