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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
89765108

O=C(Nc1n[nH]cc1)Nc1cc(F)cc(c1)F		 Formula:C10H8F2N4O
Mol: 238.19
Heavy atoms:17
Aromatic heavy atoms: 11
Fraction Csp3: 0.00
Rotatable bonds: 4
H-bond acceptors: 4
H-bond donors: 3
MR: 57.23
TPSA: 69.81
ILOGP:1.57
XLOGP3: 1.31
WLOGP: 2.79
MLOGP: 2.11
Silicos ITLogP: 1.65
Consensus LogP: 1.89
 ESOL
LogS:-2.36
Solubility(mg/ml): 1.050000
Solubility(mol/l):0.004400
Class:Soluble

Ali
LogS:-2.38
Solubility(mg/ml): 1.000000
Solubility(mol/l): 0.004200
Class:Soluble

SilicosIT
LogS:-4.37
Solubility(mg/ml): 0.010200
Solubility(mol/l): 0.000043
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.82
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.16