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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
8652428

Cc1cc(=O)[nH]c(n1)Nc1nc2c([nH]1)cccc2		 Formula:C12H11N5O
Mol: 241.25
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.08
Rotatable bonds: 2
H-bond acceptors: 3
H-bond donors: 3
MR: 69.02
TPSA: 86.46
ILOGP:0.44
XLOGP3: 0.93
WLOGP: 1.70
MLOGP: 1.39
Silicos ITLogP: 2.28
Consensus LogP: 1.35
 ESOL
LogS:-2.41
Solubility(mg/ml): 0.947000
Solubility(mol/l):0.003920
Class:Soluble

Ali
LogS:-2.33
Solubility(mg/ml): 1.120000
Solubility(mol/l): 0.004660
Class:Soluble

SilicosIT
LogS:-5.04
Solubility(mg/ml): 0.002220
Solubility(mol/l): 0.000009
Class:Moderately soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -7.11
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.16