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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
83367011

Nc1[nH+]cccc1CNc1ccc2c(c1)[nH]nc2		 Formula:C13H14N5
Mol: 240.28
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.08
Rotatable bonds: 3
H-bond acceptors: 1
H-bond donors: 4
MR: 72.98
TPSA: 80.87
ILOGP:1.43
XLOGP3: 1.61
WLOGP: 1.24
MLOGP: 1.06
Silicos ITLogP: 1.82
Consensus LogP: 1.43
 ESOL
LogS:-2.76
Solubility(mg/ml): 0.415000
Solubility(mol/l):0.001730
Class:Soluble

Ali
LogS:-2.92
Solubility(mg/ml): 0.289000
Solubility(mol/l): 0.001200
Class:Soluble

SilicosIT
LogS:-5.16
Solubility(mg/ml): 0.001660
Solubility(mol/l): 0.000007
Class:Moderately soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -6.62
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.97