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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
74330435

Nc1cnc2c(c1)[nH]c(n2)c1ccc(c(c1)F)F		 Formula:C12H8F2N4
Mol: 246.22
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.00
Rotatable bonds: 1
H-bond acceptors: 4
H-bond donors: 2
MR: 63.65
TPSA: 67.59
ILOGP:1.21
XLOGP3: 1.93
WLOGP: 3.33
MLOGP: 2.29
Silicos ITLogP: 3.08
Consensus LogP: 2.37
 ESOL
LogS:-3.13
Solubility(mg/ml): 0.181000
Solubility(mol/l):0.000736
Class:Soluble

Ali
LogS:-2.97
Solubility(mg/ml): 0.262000
Solubility(mol/l): 0.001060
Class:Soluble

SilicosIT
LogS:-5.26
Solubility(mg/ml): 0.001350
Solubility(mol/l): 0.000005
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.43
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.07