Go Back
ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
73667317

Clc1ccc(cc1)c1ncc(c(n1)[O-])C(=O)N		 Formula:C11H7ClN3O2
Mol: 248.65
Heavy atoms:17
Aromatic heavy atoms: 12
Fraction Csp3: 0.00
Rotatable bonds: 2
H-bond acceptors: 4
H-bond donors: 1
MR: 60.71
TPSA: 91.93
ILOGP:1.44
XLOGP3: 1.90
WLOGP: 2.04
MLOGP: 1.14
Silicos ITLogP: 1.73
Consensus LogP: 1.65
 ESOL
LogS:-2.97
Solubility(mg/ml): 0.267000
Solubility(mol/l):0.001070
Class:Soluble

Ali
LogS:-3.45
Solubility(mg/ml): 0.087500
Solubility(mol/l): 0.000352
Class:Soluble

SilicosIT
LogS:-3.81
Solubility(mg/ml): 0.038900
Solubility(mol/l): 0.000156
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.47
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.56
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.95