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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
72271197

O=C(c1n[nH]c(c1)C1CC1)NCc1nccs1		 Formula:C11H12N4OS
Mol: 248.30
Heavy atoms:17
Aromatic heavy atoms: 10
Fraction Csp3: 0.36
Rotatable bonds: 5
H-bond acceptors: 3
H-bond donors: 2
MR: 64.21
TPSA: 98.91
ILOGP:1.85
XLOGP3: 0.96
WLOGP: 1.46
MLOGP: 0.13
Silicos ITLogP: 3.04
Consensus LogP: 1.49
 ESOL
LogS:-2.09
Solubility(mg/ml): 2.020000
Solubility(mol/l):0.008140
Class:Soluble

Ali
LogS:-2.62
Solubility(mg/ml): 0.589000
Solubility(mol/l): 0.002370
Class:Soluble

SilicosIT
LogS:-3.66
Solubility(mg/ml): 0.054400
Solubility(mol/l): 0.000219
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -7.13
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.47