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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
71790011

Clc1cc2[nH]c(nc2cc1F)c1nccnc1		 Formula:C11H6ClFN4
Mol: 248.64
Heavy atoms:17
Aromatic heavy atoms: 15
Fraction Csp3: 0.00
Rotatable bonds: 1
H-bond acceptors: 4
H-bond donors: 1
MR: 62.09
TPSA: 54.46
ILOGP:1.87
XLOGP3: 1.77
WLOGP: 3.23
MLOGP: 1.48
Silicos ITLogP: 3.51
Consensus LogP: 2.37
 ESOL
LogS:-3.08
Solubility(mg/ml): 0.205000
Solubility(mol/l):0.000825
Class:Soluble

Ali
LogS:-2.53
Solubility(mg/ml): 0.731000
Solubility(mol/l): 0.002940
Class:Soluble

SilicosIT
LogS:-5.58
Solubility(mg/ml): 0.000648
Solubility(mol/l): 0.000003
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -6.56
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.38