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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
6942699

Cc1n[nH]c(c1)C(=O)Nc1cccc(c1C)Cl		 Formula:C12H12ClN3O
Mol: 249.70
Heavy atoms:17
Aromatic heavy atoms: 11
Fraction Csp3: 0.17
Rotatable bonds: 3
H-bond acceptors: 2
H-bond donors: 2
MR: 67.74
TPSA: 57.78
ILOGP:1.96
XLOGP3: 2.78
WLOGP: 2.74
MLOGP: 2.01
Silicos ITLogP: 3.19
Consensus LogP: 2.54
 ESOL
LogS:-3.42
Solubility(mg/ml): 0.094900
Solubility(mol/l):0.000380
Class:Soluble

Ali
LogS:-3.65
Solubility(mg/ml): 0.056000
Solubility(mol/l): 0.000224
Class:Soluble

SilicosIT
LogS:-5.15
Solubility(mg/ml): 0.001770
Solubility(mol/l): 0.000007
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -5.85
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.94