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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
63216010

Nc1nccnc1c1nc2c([nH]1)cccc2F		 Formula:C11H8FN5
Mol: 229.21
Heavy atoms:17
Aromatic heavy atoms: 15
Fraction Csp3: 0.00
Rotatable bonds: 1
H-bond acceptors: 4
H-bond donors: 2
MR: 61.48
TPSA: 80.48
ILOGP:1.49
XLOGP3: 0.80
WLOGP: 2.17
MLOGP: 0.78
Silicos ITLogP: 2.15
Consensus LogP: 1.48
 ESOL
LogS:-2.35
Solubility(mg/ml): 1.020000
Solubility(mol/l):0.004450
Class:Soluble

Ali
LogS:-2.07
Solubility(mg/ml): 1.940000
Solubility(mol/l): 0.008480
Class:Soluble

SilicosIT
LogS:-4.61
Solubility(mg/ml): 0.005610
Solubility(mol/l): 0.000025
Class:Moderately soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -7.13
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.40