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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
63215929

Clc1ccc2c(c1)nc([nH]2)c1nccnc1N		 Formula:C11H8ClN5
Mol: 245.67
Heavy atoms:17
Aromatic heavy atoms: 15
Fraction Csp3: 0.00
Rotatable bonds: 1
H-bond acceptors: 3
H-bond donors: 2
MR: 66.53
TPSA: 80.48
ILOGP:1.74
XLOGP3: 1.33
WLOGP: 2.26
MLOGP: 0.92
Silicos ITLogP: 2.37
Consensus LogP: 1.73
 ESOL
LogS:-2.79
Solubility(mg/ml): 0.400000
Solubility(mol/l):0.001630
Class:Soluble

Ali
LogS:-2.62
Solubility(mg/ml): 0.587000
Solubility(mol/l): 0.002390
Class:Soluble

SilicosIT
LogS:-4.95
Solubility(mg/ml): 0.002780
Solubility(mol/l): 0.000011
Class:Moderately soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -6.85
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.26