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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
58688165

Fc1cccc(c1)CNC(=O)c1cnc(cn1)C		 Formula:C13H12FN3O
Mol: 245.25
Heavy atoms:18
Aromatic heavy atoms: 12
Fraction Csp3: 0.15
Rotatable bonds: 4
H-bond acceptors: 4
H-bond donors: 1
MR: 64.44
TPSA: 54.88
ILOGP:2.48
XLOGP3: 1.39
WLOGP: 2.12
MLOGP: 1.02
Silicos ITLogP: 2.77
Consensus LogP: 1.96
 ESOL
LogS:-2.47
Solubility(mg/ml): 0.839000
Solubility(mol/l):0.003420
Class:Soluble

Ali
LogS:-2.15
Solubility(mg/ml): 1.750000
Solubility(mol/l): 0.007140
Class:Soluble

SilicosIT
LogS:-5.25
Solubility(mg/ml): 0.001390
Solubility(mol/l): 0.000006
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.81
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.99