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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
572766

N#Cc1[nH]c(nc1C#N)NC(=O)c1cccs1		 Formula:C10H5N5OS
Mol: 243.24
Heavy atoms:17
Aromatic heavy atoms: 10
Fraction Csp3: 0.00
Rotatable bonds: 3
H-bond acceptors: 4
H-bond donors: 2
MR: 60.11
TPSA: 133.60
ILOGP:0.09
XLOGP3: 1.35
WLOGP: 1.28
MLOGP: -0.86
Silicos ITLogP: 2.26
Consensus LogP: 0.82
 ESOL
LogS:-2.44
Solubility(mg/ml): 0.892000
Solubility(mol/l):0.003670
Class:Soluble

Ali
LogS:-3.76
Solubility(mg/ml): 0.042500
Solubility(mol/l): 0.000175
Class:Soluble

SilicosIT
LogS:-3.20
Solubility(mg/ml): 0.153000
Solubility(mol/l): 0.000630
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: No
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.83
Lipinski:0
Ghose: 0
Veber: 0
Egan: 1
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.22