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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
4999788

FC(c1ccccc1CNc1ncn[nH]1)(F)F		 Formula:C10H9F3N4
Mol: 242.20
Heavy atoms:17
Aromatic heavy atoms: 11
Fraction Csp3: 0.20
Rotatable bonds: 4
H-bond acceptors: 5
H-bond donors: 2
MR: 55.18
TPSA: 53.60
ILOGP:1.30
XLOGP3: 2.68
WLOGP: 3.25
MLOGP: 2.22
Silicos ITLogP: 2.55
Consensus LogP: 2.40
 ESOL
LogS:-3.24
Solubility(mg/ml): 0.138000
Solubility(mol/l):0.000569
Class:Soluble

Ali
LogS:-3.46
Solubility(mg/ml): 0.084400
Solubility(mol/l): 0.000348
Class:Soluble

SilicosIT
LogS:-4.73
Solubility(mg/ml): 0.004520
Solubility(mol/l): 0.000019
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -5.87
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.88