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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
49531820

COc1ccc(cc1NC(=O)c1[nH]nc(c1)C)C		 Formula:C13H15N3O2
Mol: 245.28
Heavy atoms:18
Aromatic heavy atoms: 11
Fraction Csp3: 0.23
Rotatable bonds: 4
H-bond acceptors: 3
H-bond donors: 2
MR: 69.23
TPSA: 67.01
ILOGP:2.19
XLOGP3: 2.12
WLOGP: 2.10
MLOGP: 1.18
Silicos ITLogP: 2.58
Consensus LogP: 2.03
 ESOL
LogS:-2.88
Solubility(mg/ml): 0.320000
Solubility(mol/l):0.001300
Class:Soluble

Ali
LogS:-3.16
Solubility(mg/ml): 0.170000
Solubility(mol/l): 0.000694
Class:Soluble

SilicosIT
LogS:-4.66
Solubility(mg/ml): 0.005350
Solubility(mol/l): 0.000022
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.29
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.08