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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
49319213

O=C(c1cnn[nH]1)N[C@@H]1CCc2c1cccc2F		 Formula:C12H11FN4O
Mol: 246.24
Heavy atoms:18
Aromatic heavy atoms: 11
Fraction Csp3: 0.25
Rotatable bonds: 3
H-bond acceptors: 4
H-bond donors: 2
MR: 61.48
TPSA: 70.67
ILOGP:1.57
XLOGP3: 1.30
WLOGP: 1.46
MLOGP: 1.59
Silicos ITLogP: 2.19
Consensus LogP: 1.62
 ESOL
LogS:-2.44
Solubility(mg/ml): 0.894000
Solubility(mol/l):0.003630
Class:Soluble

Ali
LogS:-2.38
Solubility(mg/ml): 1.020000
Solubility(mol/l): 0.004130
Class:Soluble

SilicosIT
LogS:-4.26
Solubility(mg/ml): 0.013400
Solubility(mol/l): 0.000054
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: Yes
CYP1A2 inhibitor: No
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.88
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.67