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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
48888736

O=C(c1cnn[nH]1)NCc1ccc2c(c1)OCO2		 Formula:C11H10N4O3
Mol: 246.22
Heavy atoms:18
Aromatic heavy atoms: 11
Fraction Csp3: 0.18
Rotatable bonds: 4
H-bond acceptors: 5
H-bond donors: 2
MR: 59.93
TPSA: 89.13
ILOGP:1.50
XLOGP3: 0.59
WLOGP: 0.31
MLOGP: 0.23
Silicos ITLogP: 1.34
Consensus LogP: 0.79
 ESOL
LogS:-1.93
Solubility(mg/ml): 2.920000
Solubility(mol/l):0.011800
Class:Very soluble

Ali
LogS:-2.04
Solubility(mg/ml): 2.270000
Solubility(mol/l): 0.009220
Class:Soluble

SilicosIT
LogS:-3.54
Solubility(mg/ml): 0.070400
Solubility(mol/l): 0.000286
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -7.38
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.28