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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
47343388

C[C@@H]1C[C@H]1C(=O)Nc1nnc([nH]1)c1ccccn1		 Formula:C12H13N5O
Mol: 243.26
Heavy atoms:18
Aromatic heavy atoms: 11
Fraction Csp3: 0.33
Rotatable bonds: 4
H-bond acceptors: 4
H-bond donors: 2
MR: 66.23
TPSA: 83.56
ILOGP:0.07
XLOGP3: 0.51
WLOGP: 1.27
MLOGP: 0.64
Silicos ITLogP: 1.56
Consensus LogP: 0.81
 ESOL
LogS:-1.86
Solubility(mg/ml): 3.380000
Solubility(mol/l):0.013900
Class:Very soluble

Ali
LogS:-1.84
Solubility(mg/ml): 3.560000
Solubility(mol/l): 0.014600
Class:Very soluble

SilicosIT
LogS:-3.77
Solubility(mg/ml): 0.041300
Solubility(mol/l): 0.000170
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: Yes
CYP1A2 inhibitor: No
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -7.42
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 3.08