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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
4385942

Nc1ccc(cc1C)c1nc2c([nH]1)cccc2		 Formula:C14H13N3
Mol: 223.27
Heavy atoms:17
Aromatic heavy atoms: 15
Fraction Csp3: 0.07
Rotatable bonds: 1
H-bond acceptors: 1
H-bond donors: 2
MR: 70.90
TPSA: 54.70
ILOGP:1.72
XLOGP3: 2.92
WLOGP: 3.13
MLOGP: 2.46
Silicos ITLogP: 3.31
Consensus LogP: 2.71
 ESOL
LogS:-3.65
Solubility(mg/ml): 0.049900
Solubility(mol/l):0.000223
Class:Soluble

Ali
LogS:-3.73
Solubility(mg/ml): 0.041600
Solubility(mol/l): 0.000186
Class:Soluble

SilicosIT
LogS:-5.46
Solubility(mg/ml): 0.000767
Solubility(mol/l): 0.000003
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -5.59
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 1
Leadlikeness: 1
Synthetic Accessibility: 1.80