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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
43519316

N#C[C@H]([S@@](=O)c1nc2c([nH]1)cc(cc2)N)C		 Formula:C10H10N4OS
Mol: 234.28
Heavy atoms:16
Aromatic heavy atoms: 9
Fraction Csp3: 0.20
Rotatable bonds: 2
H-bond acceptors: 3
H-bond donors: 2
MR: 62.27
TPSA: 114.77
ILOGP:0.31
XLOGP3: 0.55
WLOGP: 2.04
MLOGP: -0.25
Silicos ITLogP: 0.50
Consensus LogP: 0.63
 ESOL
LogS:-1.92
Solubility(mg/ml): 2.800000
Solubility(mol/l):0.011900
Class:Very soluble

Ali
LogS:-2.53
Solubility(mg/ml): 0.688000
Solubility(mol/l): 0.002940
Class:Soluble

SilicosIT
LogS:-3.10
Solubility(mg/ml): 0.187000
Solubility(mol/l): 0.000796
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: No
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -7.34
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 1
Leadlikeness: 1
Synthetic Accessibility: 3.06