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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
40835016

COC(CNC(=O)c1cc2c([nH]1)cccc2)OC		 Formula:C13H16N2O3
Mol: 248.28
Heavy atoms:18
Aromatic heavy atoms: 9
Fraction Csp3: 0.31
Rotatable bonds: 6
H-bond acceptors: 3
H-bond donors: 2
MR: 67.89
TPSA: 63.35
ILOGP:1.54
XLOGP3: 1.93
WLOGP: 1.52
MLOGP: 0.54
Silicos ITLogP: 2.02
Consensus LogP: 1.51
 ESOL
LogS:-2.57
Solubility(mg/ml): 0.669000
Solubility(mol/l):0.002700
Class:Soluble

Ali
LogS:-2.88
Solubility(mg/ml): 0.324000
Solubility(mol/l): 0.001310
Class:Soluble

SilicosIT
LogS:-4.00
Solubility(mg/ml): 0.024900
Solubility(mol/l): 0.000100
Class:Soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.44
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 1
Leadlikeness: 1
Synthetic Accessibility: 1.93