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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
394190

Cc1cc(C)nc(n1)Nc1nc2c([nH]1)cccc2		 Formula:C13H13N5
Mol: 239.28
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.15
Rotatable bonds: 2
H-bond acceptors: 3
H-bond donors: 2
MR: 71.16
TPSA: 66.49
ILOGP:1.64
XLOGP3: 2.55
WLOGP: 2.71
MLOGP: 1.74
Silicos ITLogP: 2.63
Consensus LogP: 2.25
 ESOL
LogS:-3.41
Solubility(mg/ml): 0.092100
Solubility(mol/l):0.000385
Class:Soluble

Ali
LogS:-3.59
Solubility(mg/ml): 0.061000
Solubility(mol/l): 0.000255
Class:Soluble

SilicosIT
LogS:-5.52
Solubility(mg/ml): 0.000729
Solubility(mol/l): 0.000003
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: Yes
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -5.95
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.00