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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
386455

n1ncn(c1)Nc1nc2c([nH]1)cccc2		 Formula:C9H8N6
Mol: 200.20
Heavy atoms:15
Aromatic heavy atoms: 14
Fraction Csp3: 0.00
Rotatable bonds: 2
H-bond acceptors: 3
H-bond donors: 2
MR: 54.96
TPSA: 71.42
ILOGP:0.42
XLOGP3: 1.07
WLOGP: 1.03
MLOGP: 1.03
Silicos ITLogP: 0.25
Consensus LogP: 0.76
 ESOL
LogS:-2.31
Solubility(mg/ml): 0.972000
Solubility(mol/l):0.004850
Class:Soluble

Ali
LogS:-2.16
Solubility(mg/ml): 1.380000
Solubility(mol/l): 0.006900
Class:Soluble

SilicosIT
LogS:-3.12
Solubility(mg/ml): 0.150000
Solubility(mol/l): 0.000750
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.76
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.19