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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
384465

O=C(c1cc2c([nH]1)cccc2)Nc1ccccc1
Formula:C15H12N2O
Mol: 236.27
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.00
Rotatable bonds: 3
H-bond acceptors: 1
H-bond donors: 2
MR: 72.51
TPSA: 44.89
ILOGP:2.11
XLOGP3: 3.62
WLOGP: 3.23
MLOGP: 2.37
Silicos ITLogP: 3.18
Consensus LogP: 2.90
ESOL
LogS:-4.00
Solubility(mg/ml): 0.023400
Solubility(mol/l):0.000099
Class:Moderately soluble

Ali
LogS:-4.25
Solubility(mg/ml): 0.013300
Solubility(mol/l): 0.000056
Class:Moderately soluble

SilicosIT
LogS:-5.81
Solubility(mg/ml): 0.000368
Solubility(mol/l): 0.000002
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  Yes
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -5.17
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 2
Synthetic Accessibility: 1.71