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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
35247731

O=C(c1cc2c([nH]1)cccc2)Nc1c[nH]nc1		 Formula:C12H10N4O
Mol: 226.23
Heavy atoms:17
Aromatic heavy atoms: 14
Fraction Csp3: 0.00
Rotatable bonds: 3
H-bond acceptors: 2
H-bond donors: 3
MR: 64.66
TPSA: 73.57
ILOGP:0.91
XLOGP3: 1.91
WLOGP: 1.95
MLOGP: 0.75
Silicos ITLogP: 2.17
Consensus LogP: 1.54
 ESOL
LogS:-2.86
Solubility(mg/ml): 0.314000
Solubility(mol/l):0.001390
Class:Soluble

Ali
LogS:-3.08
Solubility(mg/ml): 0.189000
Solubility(mol/l): 0.000835
Class:Soluble

SilicosIT
LogS:-4.65
Solubility(mg/ml): 0.005110
Solubility(mol/l): 0.000023
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  No
Log kp:  -6.32
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.85