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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
35165147

COC(=O)CNC(=O)c1cn2c(n1)cccc2C		 Formula:C12H13N3O3
Mol: 247.25
Heavy atoms:18
Aromatic heavy atoms: 9
Fraction Csp3: 0.25
Rotatable bonds: 5
H-bond acceptors: 4
H-bond donors: 1
MR: 64.05
TPSA: 72.70
ILOGP:2.54
XLOGP3: 1.69
WLOGP: 0.55
MLOGP: 0.19
Silicos ITLogP: 0.71
Consensus LogP: 1.14
 ESOL
LogS:-2.48
Solubility(mg/ml): 0.823000
Solubility(mol/l):0.003330
Class:Soluble

Ali
LogS:-2.83
Solubility(mg/ml): 0.364000
Solubility(mol/l): 0.001470
Class:Soluble

SilicosIT
LogS:-2.96
Solubility(mg/ml): 0.271000
Solubility(mol/l): 0.001100
Class:Soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.61
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.16