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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
35149435

O=C(c1cc2c([nH]1)cccc2)Nc1ncccn1		 Formula:C13H10N4O
Mol: 238.24
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.00
Rotatable bonds: 3
H-bond acceptors: 3
H-bond donors: 2
MR: 68.10
TPSA: 70.67
ILOGP:1.71
XLOGP3: 2.23
WLOGP: 2.02
MLOGP: 0.99
Silicos ITLogP: 2.08
Consensus LogP: 1.81
 ESOL
LogS:-3.14
Solubility(mg/ml): 0.172000
Solubility(mol/l):0.000723
Class:Soluble

Ali
LogS:-3.35
Solubility(mg/ml): 0.107000
Solubility(mol/l): 0.000447
Class:Soluble

SilicosIT
LogS:-5.06
Solubility(mg/ml): 0.002060
Solubility(mol/l): 0.000009
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  No
Log kp:  -6.17
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.76