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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
35127576

O=C(c1cc2c([nH]1)cccc2)Nc1nccs1		 Formula:C12H9N3OS
Mol: 243.28
Heavy atoms:17
Aromatic heavy atoms: 14
Fraction Csp3: 0.00
Rotatable bonds: 3
H-bond acceptors: 2
H-bond donors: 2
MR: 68.18
TPSA: 86.02
ILOGP:1.83
XLOGP3: 2.98
WLOGP: 2.69
MLOGP: 1.18
Silicos ITLogP: 3.28
Consensus LogP: 2.39
 ESOL
LogS:-3.64
Solubility(mg/ml): 0.056100
Solubility(mol/l):0.000231
Class:Soluble

Ali
LogS:-4.45
Solubility(mg/ml): 0.008630
Solubility(mol/l): 0.000036
Class:Moderately soluble

SilicosIT
LogS:-4.70
Solubility(mg/ml): 0.004810
Solubility(mol/l): 0.000020
Class:Moderately soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  Yes
CYP2C9:  Yes
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -5.67
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.15