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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
34519267

O[C@@H](C(F)(F)F)C(=O)Nc1ccccc1		 Formula:C9H8F3NO2
Mol: 219.16
Heavy atoms:15
Aromatic heavy atoms: 6
Fraction Csp3: 0.22
Rotatable bonds: 4
H-bond acceptors: 5
H-bond donors: 2
MR: 46.91
TPSA: 49.33
ILOGP:1.25
XLOGP3: 1.59
WLOGP: 2.62
MLOGP: 1.41
Silicos ITLogP: 1.53
Consensus LogP: 1.68
 ESOL
LogS:-2.23
Solubility(mg/ml): 1.280000
Solubility(mol/l):0.005850
Class:Soluble

Ali
LogS:-2.24
Solubility(mg/ml): 1.270000
Solubility(mol/l): 0.005790
Class:Soluble

SilicosIT
LogS:-2.77
Solubility(mg/ml): 0.376000
Solubility(mol/l): 0.001720
Class:Soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: No
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.51
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.59