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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
32726043

O=C(c1cc2c([nH]1)cccc2)Nc1ccncc1		 Formula:C14H11N3O
Mol: 237.26
Heavy atoms:18
Aromatic heavy atoms: 15
Fraction Csp3: 0.00
Rotatable bonds: 3
H-bond acceptors: 2
H-bond donors: 2
MR: 70.31
TPSA: 57.78
ILOGP:1.62
XLOGP3: 2.55
WLOGP: 2.62
MLOGP: 1.27
Silicos ITLogP: 2.63
Consensus LogP: 2.14
 ESOL
LogS:-3.34
Solubility(mg/ml): 0.109000
Solubility(mol/l):0.000461
Class:Soluble

Ali
LogS:-3.41
Solubility(mg/ml): 0.092200
Solubility(mol/l): 0.000388
Class:Soluble

SilicosIT
LogS:-5.43
Solubility(mg/ml): 0.000871
Solubility(mol/l): 0.000004
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  No
CYP2C9:  No
CYP2D6:  Yes
CYP3A4:  Yes
Log kp:  -5.94
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.74