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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
25269241

CNC(=O)CNC(=O)c1cc2c([nH]1)ccc(c2)F		 Formula:C12H12FN3O2
Mol: 249.24
Heavy atoms:18
Aromatic heavy atoms: 9
Fraction Csp3: 0.17
Rotatable bonds: 5
H-bond acceptors: 3
H-bond donors: 3
MR: 63.87
TPSA: 73.99
ILOGP:1.23
XLOGP3: 1.11
WLOGP: 1.20
MLOGP: 0.60
Silicos ITLogP: 1.94
Consensus LogP: 1.22
 ESOL
LogS:-2.12
Solubility(mg/ml): 1.870000
Solubility(mol/l):0.007510
Class:Soluble

Ali
LogS:-2.26
Solubility(mg/ml): 1.380000
Solubility(mol/l): 0.005540
Class:Soluble

SilicosIT
LogS:-4.36
Solubility(mg/ml): 0.010900
Solubility(mol/l): 0.000044
Class:Moderately soluble
GIAbsorption:High
BBB permeant: No
Pgp substrate: No
CYP1A2 inhibitor: No
CYP2C19:  No
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -7.03
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 1.85