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ZINC ID                   RADAR Physiochemical Propperties Lipophilicity Water solubility Phyarmacokinetics Druglikeness Medicinal Chemistry
22538237

COc1ccc(cc1NC(=O)c1coc(n1)C)C		 Formula:C13H14N2O3
Mol: 246.26
Heavy atoms:18
Aromatic heavy atoms: 11
Fraction Csp3: 0.23
Rotatable bonds: 4
H-bond acceptors: 4
H-bond donors: 1
MR: 67.14
TPSA: 64.36
ILOGP:2.57
XLOGP3: 2.24
WLOGP: 2.36
MLOGP: 0.77
Silicos ITLogP: 2.45
Consensus LogP: 2.08
 ESOL
LogS:-2.97
Solubility(mg/ml): 0.266000
Solubility(mol/l):0.001080
Class:Soluble

Ali
LogS:-3.23
Solubility(mg/ml): 0.146000
Solubility(mol/l): 0.000593
Class:Soluble

SilicosIT
LogS:-4.66
Solubility(mg/ml): 0.005340
Solubility(mol/l): 0.000022
Class:Moderately soluble
GIAbsorption:High
BBB permeant: Yes
Pgp substrate: No
CYP1A2 inhibitor: Yes
CYP2C19:  Yes
CYP2C9:  No
CYP2D6:  No
CYP3A4:  No
Log kp:  -6.21
Lipinski:0
Ghose: 0
Veber: 0
Egan: 0
Muegge: 0
Bioavalability Score0.55
PAINS:0
Brenk: 0
Leadlikeness: 1
Synthetic Accessibility: 2.49